A: Jim, there's something wrong with my computer. Can you give me a hand?
B: Sure. What's wrong?
A: I don't know. Could you come and help me mend it?
B: Certainly, but not today. How about Wednesday evening?
A: OK. Thanks a lot. See you then.
give a hand (with)
变异：give sb. a hand
exp. To help someone with something. （帮某人做某事，帮助）
e.g.I hope that someone will give me a hand with these bags—there's no way I'll make it to the fifth floor on my own!
e.g. No, Billy can't babysit, he's giving me a hand with my car today.
e.g. I would have liked him to give me a hand, but found it embarrassing to ask.
e.g. He is in trouble now, and we ought to give him a hand.
There is something wrong with....
e.g. There is something wrong with the radio, and I can't get it right.
What is wrong with...？
e.g. What is wrong with their products?
e.g. How about cleaning up a bit around here?